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NLRP3 is an intracellular sensor that detects a broad range of PAMPs as well as self- and foreign-derived DAMPs, such as ATP, cholesterol crystals, oxidized mitochondrial DNA, cyclic GMPAMP, and nanoparticle, resulting in the formation and activation of the NLRP3 inflammasome 45)

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When ingested, psilocybin is converted to psilocin in the body, and both substances have hallucinogenic effects