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Overall, these data suggest that SDH inhibition suppresses ATCase activity and aspartate consumption into pyrimidine synthesis in FH-KO cells by increasing succinate levels

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Researchers have hypothesized several mechanisms by which food insecurity may lead to obesity, including increased consumption of unhealthy diet, stress and anxiety generating higher levels of stress hormones, which heighten appetite, and a physiological response to reduced food availability leading to higher fat storage in the body (127)