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[87] This trial was the first to report a survival advantage from chemotherapy in malignant pleural mesothelioma, showing a statistically significant improvement in median survival from 10 months in the patients treated with cisplatin alone to 13.3 months in the group of patients treated with cisplatin in the combination with pemetrexed and who also received supplementation with folate and vitamin B 12
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The workers exposed to asbestos for 10 years to 30 years were classified as medium asbestos exposure and those with more than 30 years were classified as high asbestos exposure
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