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The two studies were part of Jouko Miettunen's research project "Trends and interactions of risk factors in psychotic disorders - Northern Finland birth cohort studies 1966 and 1986", which was funded by the Academy of Finland

The content of the counseling record form was written based on the counselors consultations with individual participants in a face-to-face manner or over the phone during the service period The collected data was analyzed using SPSS 24.0 to examine differences in the characteristics of participants between people who resumed smoking within 6 months and those who continuously abstained from smoking for 6 months, examine the patterns of smoking relapse according to the duration of smoking abstinence, and identify factors associated with smoking relapse within 6 months

The analysis identified the emergence of four distinct clusters

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Furthermore, we observed increased protein levels of OXPHOS components and increased levels of the oxidative stress marker and anti-oxidant Mn-SOD, indicating augmented energy demand and oxidative stress