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Symptoms include: Leg, ankle and feet weakness and Decreased ability to run High foot arches Curled toes (hammertoes) Loss of muscle bulk in legs and feet Regular tripping or falling Trouble lifting feet at the ankle Reduced or loss of sensation in legs and feet Awkward or higher than usual step

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The FDA issued a warning letter in July 2020 to the makers of Puff Bar vape, ordering the company to stop selling its disposable flavored e-cigarettes as it did not have the required premarket authorization

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Cigarette smoking - United States, 1965-2008