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Such epigenetic alterations, primarily DNA methylation, histone modification and the regulation of gene expression by microRNAs (miRNAs/miRs), serve a crucial role in fetal development, particularly through their impact on the placenta, an organ fundamental to nutrient and oxygen exchange during pregnancy (2,3)

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It was found that oocyte production lowered along with increased basal FSH levels ( p 25 kg/m2, and in women over 35 [5]

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This shrinkage is largely due to toxic chemicals in cigarettes, including nicotine and carbon monoxide, which restrict blood flow to the brain and decrease oxygen supply to brain cells