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The statistical significance of differences between the glaucoma group and the control group was determined with the Students t test or Fishers exact test

For mTYR, the narrow dual copper-binding site makes it more difficult for arbutin, which has two rings, to fit, especially in the MD-stable conformation of Arbutin_b, where the number of hydrogen bonds between arbutin and the pocket is much lower than in other conformations (Table 2)

[ 309 ] Another study suggests a thermosensitive gelnano system for EC treatment through small interfering RNA targeting BACH1 and p53 activator PRIMA1, restoring antitumor immune responses, has potential for clinical application

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