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These items have only recently been accepted into the mainstream of traditional smoke shops

Gale N, McEwan M, Camacho OM, Hardie G, Proctor CJ, Murphy J (2021) Changes in biomarkers after 180 days of tobacco heating product use: a randomised trial

Its short effects include irritation of the eyes and the respiratory tract, with the long term exposure causing asthma and weaker cardiovascular function

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Neutrophils Neutrophils are a short-lived cell with a half-life in the circulation of approximately 1.512.5 h in mice [100]