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After the two travelers were properly introduced, Birkin helped design Jean-Louiss most famous contribution to the Herms canon: the Birkin bag, a roomy, square catchall with the HACs trademark leather flap top and the addition of a lock and key

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Nicotine is known to increase adrenaline levels, a hormone associated with the "fight or flight" response, leading to a rise in heart rate and blood pressure

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