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For significant differences, the difference between the two groups' averages would be large and its corresponding p-value would be small

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Headache 63(10):13411350 Sarker MAB, Rahman M, Harun-Or-Rashid M, Hossain S, Kasuya H, Sakamoto J et al (2013) Association of smoked and smokeless tobacco use with migraine: a hospital-based case-control study in Dhaka, Bangladesh