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When tested in normal human volunteers, it was found to exert sedative properties, but when tested in ~500 patients with various psychiatric disorders, only those with endogenous depression exhibited a remarkable improvement of clinical symptoms after 1-6 weeks of daily treatment

If we rely on the 18th-century cartographer John Rocque, major wooded areas had vanished from the Colliers Wood area by the middle of the century, but there is no reason to question the origin of the name

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