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Abbreviations ACE2: Angiotensin-converting enzyme 2 Ang-1-7: Angiotensin 1-7 BALF: Bronchoalveolar lavage fluid CAD: Cinnamaldehyde CDC: US Centers for Disease Control and Prevention CO: Carbon monoxide COPD: Chronic obstructive pulmonary disease COVID-19: Coronavirus disease 2019 CS: Cigarette smoke ENDS: Electronic nicotine dispensing systems EVALI: e-cigarette or vaping product use-associated lung injury FDA: Food and Drug Administration GC-FID: Gas chromatography with a flame ionisation detector GCMS: Gas chromatography-mass spectrometry GM-CSF: Granulocytemacrophage colony-stimulating factor HPLC: High performance liquid chromatography HUVEC: Human umbilical vein endothelial cells IL: Interleukin IFN: Interferon KO: Knockout LCMS: Liquid chromatography-mass spectrometry MCP-1/CCL2: Monocyte chemoattractant protein-1 MMP-9: Matrix metallopeptidase 9 nAChR7: 7 Nicotinic acetylcholine receptor NC: Nickelchromium alloy NO: Nitric oxide PG: Propylene glycol RANTES/CCL5: Regulated on activation, normal T cell expressed and secreted ROS: Reactive oxygen species SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2 SS: Stainlesssteel atomizer THC: Tetrahydrocannabinol TNF: Tumour necrosis factor- WT: Wild type References Hiemstra PS, Bals R

"Beaucoup de personnes pensent que fumer quelques cigarettes par jour nest pas si mauvais pour la sant", explique Elizabeth Oelsner, chercheuse et directrice de cette tude publie dans The Lancet (nouvelle fentre)

They simply have not been on the market long enough for public health officials to make an informed decision about a product that contains so many known toxins