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tobacco industry spent $13.5 billion on tobacco advertising and promotion,[1] while in 2006, the five largest cigarette manufacturers spent a total of $12.49 billion to promote and advertise their products.[2] Evidently, in a competitive marketplace, each firm is willing to engage in significant congressional lobbying and expenditure to capture a significant portion of American cigarette consumers

CB1 receptors are heavily distributed in the Central Nervous System (CNS)

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