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Firstly, the chemicals in cigarette smoke can irritate and inflame the lining of the urinary tract, creating an environment conducive to infection

doi: 10.1016/j.marpolbul.2020.111633 2 AkhbarizadehR.DobaradaranS.ParhizgarG.SchmidtT

They found the highest NOAEL was 500 mg/kg for guinea pigs and 15 g/kg for rats for 1 month of oral administration

Flavoured cigarettes do not reduce health risks associated with smoking