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As a result, smokers face a much higher risk for both acute and chronic bronchitis
The partnership continued to be very successful and the business grew substantially
Chronic exposure to tobacco smoke or nicotine leads to tolerance to the physiological (e.g., decrease in heart rate and body temperature) and behavioral (e.g., decrease in locomotor activity and rearing) effects of nicotine and an upregulation of 42 and 7-containing nAChRs in rats and mice (Pauly et al., 1991
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