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Therefore, IGF-1 levels further drop and, due to the lack of negative feedback by IGF-1 on the hypothalamus, growth hormone (GH) levels increase significantly

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In order to reduce the age-related damage of oocytes caused by prolonged culture in vitro , it is necessary to find an agent that has no negative effect on oocyte development and can effectively delay the aging damage caused by the accumulation of ROS

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