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Cholesterol accumulation in macrophages is associated with their proinflammatory activation through several mechanisms, including the effect on the structural organization of cell plasma membranes and the structure of lipid rafts

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Although much research focuses on effects of specific messages and is often concerned about single instances of pro-tobacco content, our focus finds that media coverage writ large is negative and predicts reduced use. Funding for the research came from the National Cancer Institute of the National Institutes of Health and the Food and Drug Administration Center for Tobacco Products (Grant P50CA179546)