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Itll depend on the medication you end up using: for example, dont stop or decrease your smoking until at least one week on Champix to ensure there is enough time for the medication to build up in your body and start working

[156] [159] [161] Combining smoking-cessation medication with behavioral therapy is more than twice as likely to be effective in helping people with COPD stop smoking, compared with behavioral therapy alone

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Smoking can also reduce the amount of high-density lipoproteins (HDL), or good cholesterol, in the bloodstream