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However, the lack of effect on total nicotine exposure indicates VLNC noncompliance, suggesting that smokers with SMI may respond to a reduced-nicotine standard by substituting alternative forms of nicotine." "Additional doseresponse relationships have been detected on the number of cigarettes smoked per day when low and high nicotine Spectrum cigarettes are available

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Nashville: Raymond Street Publishers, 2012

4,8 Consuming nicotine too close to bedtime can keep you from falling asleep due to the drugs stimulant properties