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However, research on smoking as a risk factor for LUTS has been inconclusive, with some studies finding that current-smokers are at greater risk of developing LUTS than non-smokers 9,10 and others reporting no association or a possible inverse relationship between current-smoking and LUTS 11,12

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While we still dont know exactly how long-lived the impact of smoking is, or whether it can be reversed, theres some good news: After quitting, the effect of smoking on the immune response seems to fade with time