suggested that QE coordinately activated autophagy and combated exosomes release by restoring lysosome function, and further mitigated ethanol-induced liver damage ( 2.7.1.4 Effects of QE on liver fibrosis In an experiment conducted by Hernandez et al., treatment with QE prevented liver injury in an animal model of CCl 4 -induced cirrhosis by increasing CB2 expression, reducing CB1 expression, promoting apoptosis of HSC and decreasing the number of activated HSCs (Li et al., 2016)
[1] [3] A family of histone deacetylases known as sirtuins (Sirt 1-7) controls a number of proteins involved in cellular metabolism, stress responses, circadian rhythms, and endocrine functions
doi:10.3390/ijerph17113782 [PubMed] 54
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[DOI] [PMC free article] [PubMed] [Google Scholar] 172.Kamphorst BE, Stoll D, Gressner AM, Weiskirchen R