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Why Some People Quit Easier Than Others Genetic factors significantly influence cessation success rates and optimal treatment selection: Metabolism Rate : Slow nicotine metabolizers often respond better to nicotine replacement therapy and may need lower doses, while fast metabolizers might benefit from combination therapies or longer treatment duration

Exposure and metabolic activation biomarkers of carcinogenic tobacco-specific nitrosamines

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Among people aged 12 or older, the percentage who were heavy alcohol users in the past month declined from 5.7 percent (or 16.1 million people) in 2021 to 5.0 percent (or 14.5 million people) in 2024 ( Figure 10 and Table A.3B )

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