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Reid, K.V

doi: 10.1016/j.tcb.2020.06.003 52 LourenoJDItoJTMartinsMATibrioIFLCLopesFDTQDS

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We have shown that IRAK4 inhibition significantly reduced the recruitment of neutrophils, specifically the N5 subset, and MoAM as well as key MoAM- and neutrophil-associated inflammatory mediators such as CCL2/CCL7 and IL-1/TNF- that are required to establish and maintain (smoke-induced) pulmonary inflammation and tissue remodeling/emphysema (12, 22, 72)

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