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Dumping syndrome is caused by different contributing factor, including: changing how food empties the stomach, how the nerves are distributed to the stomach, and the stimulation of gastrointestinal hormones

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Taken together, it is possible that nicotine plus a HFD through changes in SCFAs metabolism, increased intestinal permeability and LPS activation of TLRs and inflammasomes, endogenous ethanol production, decreased choline availability and trimethylamine production could cause NAFLD