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Using Spearman's rank correlation, degrees of associations between U-tAs and U-8OHdG, U-tAs and S-8OHdG and U-8OHdG and S-8OHdG were investigated

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"My billing was always 'Pee-wee Herman as Himself.'" In 1985, Pee-wee headlined his very own movie with "Pee-wee's Big Adventure." Reubens' would subsequently star as the character on the children's programming series "Pee-wee's Playhouse" between 1986 and 1990, along with a cinematic sequel in 1988's "Big Top Pee-wee." Reubens sporadically returned to Pee-wee Herman in subsequent decades While Paul Reubens' turned Pee-wee Herman into a bona fide pop culture phenomenon in the 1980s, the actor and his beloved character wouldn't take part in any significant new projects for years