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Relationship between the cytotoxicity of each refill fluid at a 1% concentration and each authentic standard chemical Each highly cytotoxic refill fluid contained one or more of the six toxic flavor chemicals at concentrations that were as cytotoxic as authentic standards in the MTT assay (Fig

Pharmacological interventions for smoking cessation: an overview and network metaanalysis

Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO (1991)

Reduced Oxygen Exchange: Smoking damages alveoli, the tiny air sacs in your lungs where oxygen and carbon dioxide are exchanged

Thus, the estimated net smuggling numbers for Delaware and the states that surround it do not "cancel out" as might be expected absent consideration of other state smuggling flows