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5 Despite the fact that the pathological characteristics of OA involve impairment of the entire joint structure, including remodeling of subchondral bone, osteophyte formation, and synovial inflammation, 6 the primary pathological hallmark remains cartilage damage

Regular stress management practices (meditation, deep breathing, exercise, adequate social connection) reduce mast cell hyperactivation through neuroimmune pathways

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Combining it with other antioxidants like vitamin C and E can create synergistic effects