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Additionally, nicotine affects other neurotransmitters and brain chemicals, such as norepinephrine and serotonin, which regulate mood, appetite, and other physiological processes

However, a randomized, controlled trial in rabbits, which display reactions similar to those of human beings, showed no additional benefit compared with the control group

pathology 17 (3), 513516

Does nicotine influence cytokine profile and subsequent cell cycling/apoptotic responses in inflammatory bowel disease

For a new VA/Per smoker, I'd rather recommend Astley's #2 for a medium-weight yet approachable introduction or Haddo's for its complexity and depth