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Physiology of GIPa lesson from GIP receptor knockout mice

FDA advisory committee votes to add popular peptide BPC-157 to drug compounding list The vote is non-binding and still needs sign-off from the FDA

The single human musculoskeletal paper that gets cited often is a small retrospective case series of intra-articular BPC-157 injections for multiple types of knee pain. It reported improvement in 11 of 12 patients, but the study has major limitations: no control group, no standardized objective outcome measures, no imaging confirmation of pathology, and unclear diagnostic specificity

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Overcoming these obstacles through further research is critical to the development of effective novel therapies in the future