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Patients were excluded if they were unable to provide informed consent due to psychiatric or cognitive impairment, medically unstable, or lacked reliable telephone access

With tobacco products, the risk of certain cancers derives from carcinogens (substances known to cause cancer), which result from: Growing of tobacco, such as arsenic, a carcinogen found naturally in soil and pesticides Curing of the tobacco leaves, which produces tobacco-specific nitrosamines Smoking of the plants leaves, which leads to the formation of formaldehyde Nicotine itself is not a known carcinogen, but it can cause cardiovascular disease, including heart disease, and can reduce saliva production