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Dual Use: A Great Risk Individuals who combine vaping and smoking expose themselves to lung cancer that is 3-4 times greater as compared to isolated smoking

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As a consequence of the stimulation due to nicotine, sympathetic neuronal discharge-impaired nitric oxide production increases in the central nervous system, which in turn leads to an increase in arterial stiffness 44-46

The landmark study published in 2003 by Vogelzang and colleagues compared cisplatin chemotherapy alone with a combination of cisplatin and pemetrexed (brand name Alimta) chemotherapy in patients who had not received chemotherapy for malignant pleural mesothelioma previously and were not candidates for more aggressive "curative" surgery