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Noteworthy, rat models tend to develop many aspects related to MS when treated with arsenic, including insulin resistance, proatherogenic dyslipidemia, non-alcoholic liver steatosis, heart damage and hypertension, while mouse models seem to develop glucose intolerance and beta cell failure, without developing dyslipidemia and insulin resistance ( Table 1 )

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[29] Nicotine may result in arousal and wakefulness, mainly via incitement in the basal forebrain

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