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The dimeric kappa GST isoenzymes found in the mitochondria of mammals are made up of 226 amino acid subunits

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In the subsequent phase III STEP trials of semaglutide, 2.4 mg once weekly, carefully up-titrated over 20 weeks, average weight losses of up to 18% were achieved over 68 weeks in people with obesity (start weight 107 kg) [40]

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