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Patients are randomized through an impartial method (usually a computer program) which will randomly place patients into any of the test groups

In addition, 2 non-nicotine prescription drugs (varenicline and bupropion) have been approved for treating tobacco dependence

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At this point, it is important to note that further discussion of club cell subsets will utilize the perspective of describing differential expression of genes among the club cell subclusters, but all of the cells in the ensuing analysis were initially clustered with club cells in the original unsupervised assessment of expression levels of ~30,000 genes in a total of over 11,000 cells (Supplementary Table 4)

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