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Conclusions In conclusion, Cytobacillus oceanisediminis C4 and Bacillus subtilis B1 isolated from tobacco could play a key role in the fermentation process of different tobacco morphologies (TP and TL) by regulating chemical composition, improving aroma components, and changing tobacco surface structure and tobacco microbiota

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Tobacco use remains the nations leading cause of preventable death and disease, taking 480,000 lives every year