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The suddenness of these cases and their geographic clustering suggest that the cause is not something inherent to commercial e-cigarettes, which have been widely used in multiple countries for more than a decade

Considering that most of the macrophages within the lungs are associated with tissue, analysis of alveolar macrophages harvested by BAL may not represent all the phenotypes of macrophages in the lung

Making cigarettes and other combusted tobacco products minimally addictive or non-addictive would help save lives

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