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Tobacco products also contain acetaldehyde, which increases the addictive effects of nicotine, evidence such as a 2007 paper by Talhout et al., from European Neuropsychopharmacology confirms

Nicotine is unique in the drug world because it can act as both a stimulant or a depressant and it can have different effects on different people

The others were smuggled from jurisdictions with much lower taxes, such as Georgia (37 cents per pack), Virginia (60 cents per pack), or else entirely bypassed the legal and taxed supply chain

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The first generations of ENDS contained primarily freebase (unprotonated) nicotine, known to be alkaline, resulting in greater harshness and a less desirable experience upon inhalation [26]