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Regardless of bottle choice, we recommend storing your serum away from heat and direct sunlight

Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease

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Because vitamin B12 is water-soluble, your body naturally eliminates any excess, making this a low-risk solution for most people