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doi:10.1136/tobaccocontrol-2014-052072 49
Such methodologies should allow for a direct comparison of (i) toxicant emissions, (ii) a broad range of toxicity endpoints and (iii) reductions in toxicant exposure, to ensure that a given cMRTP is equivalent to, or better than, the reference MRTP
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For example, the importance of tobacco weight in determining mainstream tar and nicotine yields has been demonstrated (Yamamoto et al.1984) and is likely a determinant of sidestream emissions, although other features of cigarette design also influence emission levels and product quality (Health Canada2004)
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