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Nevertheless, determining the appropriate age at which to allow individuals to vape and purchase these products, deciding on penalties for retailers who break the law, and establishing effective methods for enforcing age restrictions present formidable challenges for legislators

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The authors said that while there have been some concerns that quitting smoking makes it more difficult to quit or stay off illicit drugs, cigarette abstinence does not appear to lead to a compensatory increase in other drug use, and may even improve drug abstinence. The authors noted that cigarette smoking is just one of many potential factors associated with SUD relapse, and that more data are needed to determine the clinical significance of the association

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