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Several devices are currently marketed, the most widespread being the IQOS (PMI), acronym for I Quit Ordinary Smoking,2,3 by 2022, PMI was promoting it in nearly 60 countries.4 IQOS was first sold in Japan in December 2013,5 which quickly became a best-seller after being advertised on a popular Japanese television show.6 Three years later, in Italy, 329,000 people who had not previously been smokers, used HNB,7 demonstrating that heated tobacco can initiate and maintain an addictive process to nicotine

Others said people use tobacco because they are bored or because there is nothing else to do

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Nicotine Addiction Many e-liquids contain nicotine, which is highly addictive and can lead to dependence on vaping products