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While data are limited, the agency does not expect non-smokers to start using the reduced nicotine products, and those who do are unlikely to develop nicotine dependence, the agency stated

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You need long-term studies that image the brain where you follow people over the years and look with each person how their brain changes in response to their use pattern. Maxwell thinks we need to learn more about how marijuana affects people not just physiologically but also mentally and spiritually

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