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Although we detected no difference between the sebum of healthy smokers and smokers with acne, it could be hypothesized that smoking is associated with a higher susceptibility to acne and in particular to APAA

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Only two of the included studies were funded by or had associations with tobacco companies 41,45 , while three studies 23,24,37 did not specify whether they had such association (see Table 1 and Supplementary file Material 4)

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