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BMC Med (2012) 10:99

When you take a puff of a cigarette, nicotine and other harmful substances enter your lungs, these deadly chemicals get absorbed into the blood

Christopher McCandless So now I'm left with cigarettes, and I'm trying to scrape that off my shoe and then I'll be done

Mario could not live with another version of himself. Arturo Sighinolfi, his new business partner, was, it seems, not so different, and, nine months into the enterprise, their partnership collapsed

But if you walk into a Sainsbury's or a Morrisons you may well see adverts for iQos, a device that uses an electric current to heat tobacco