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On the other hand, opposite results, downregulation of filaggrin was observed in reconstructed human epidermis exposed to cigarette smoke as well 22

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who demonstrated that exposure of HBEC to e-cig aerosols of PG/VG (55:45 ratio) caused a significant increase in MUC5AC expression independent of the presence of nicotine 46

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Juul agreed to a settlement in 2022, but the Altria settlement, which was needed to kickstart payouts, was not approved until earlier this year