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Inject the bacteriostatic water slowly, directing it down the inside wall of the vial rather than directly onto the powder

Statistical significance was assessed by ordinary One-Way ANOVA followed by Dunnetts multiple comparisons test in b , c , d

Funding This research received no specific grant from any funding agency or the commercial or not-for-profit sectors

During development and progression of atherosclerosis, Nrf2 signaling modulates many physiological and pathophysiological processes, like regulation of lipid homeostasis, CD36 gene expression regulation, foam cell formation, macrophage polarization, immunity regulation (Th2 differentiation and inhibition of pro-inflammatory gene expression through NFB down-regulation), redox regulation and inflammation, improvement of endothelial dysfunction, as well as GSH synthesis and utilization (234245)