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Human peripheral blood lymphocytes (PBLs) of healthy donors (HD) were isolated as described [48] from buffy coats, obtained from the Madrid Blood Donor Centre (Madrid, Spain), and then stimulated with 5 g/ml leucoagglutinin (L4144

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14) indicated that the dimeric macrocycles and hHGF all promoted DNA synthesis, but that aMsD4-C6 did not