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Buck Duke, it should be noted, went on to found the precursor to Duke Energy and made generous financial contributions to various nonprofit, religious, and educational organizations, including his namesake university in North Carolinaformerly Trinity College

However, the mechanistic understanding (summarised in Table 1) of how maternal smoking adversely affects offspring has also been drawn from research using pure nicotine due to the complex confounding variables in humans (Ernst et al., 2001)