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164,165,166,167 Similarly, DNA damage induces the relocalization of NAD + -dependent deacetylase SIRT1 to DNA breaks, which promotes DNA repair via opening the chromatin and recruiting the main DNA repair factors including KU70, NBS1, WRN, KAP1, XPA and APEX1

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Both in vitro and in vivo studies in rat tendons have shown that BPC-157 promotes collateralization and increases fibroblast density in the event of injuries to tendons, ligaments and bones

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways