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The study revealed: Decreased melanin content : Measured by mexameter, a device that quantifies melanin, Pynocare led to a notable decrease in skin pigmentation
In this study, we utilized the acrylamide warhead, renowned for its biocompatibility due to its low non-specific reactivity towards thiol groups, which necessitates an optimal orientation of the acrylamide warhead towards the target cysteines after the initial association step and in the reversibly bound state 3,35